Developmental and Structural Section
Wuersig, Renate , Zanis, Michael .
The Natural History of C-class Genes: Independent Duplication Events in Diverse Angiosperm Lineages.
Gene and genome duplications are widespread phenomena that have occurred throughout the tree of life. In angiosperms, single gene and whole genome duplications (paleopolyploidy events) have resulted in the elaboration and diversification of multiple pathways, including developmental pathways. Well-documented duplications of floral homeotic genes have been identified at the base of the angiosperms and along specific angiosperm lineages. As a result, it is apparent that many of the genes that comprise the ABC(DE)-model of flower development are the product of both ancient and recent gene/genome duplication events. C class MADS-box genes, which specify stamen and carpel identity, have independently duplicated in numerous angiosperm lineages. We hypothesize that function of duplicated C class floral development genes have been diversified via partitioning (i.e. subfunctionalization) or evolution of new functions (neofunctionalization). While post-duplication subfunctionalization has been largely attributed to mutations in key regulatory sequences such as promoters, changes due to mutations in protein coding regions of duplicate genes should also be considered. Post-duplication changes in both coding and non-coding regions offer valuable insight into the different mechanisms by which genes can alter their function and expression patterns through evolutionary time. Using phylogenetic, gene expression and transgenic methodologies, we seek to identify the relative timing of gene duplication events and the mutational changes that have maintained duplicate C class genes. Our work will provide functional insight into the relative timing and evolutionary dynamics of how independently duplicated genes have been maintained across diverse angiosperm lineages.
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1 - Purdue University, Botany and Plant Pathology, 915 West State Street, Purdue University, West Lafayette, IN, 47907-2054, USA
Presentation Type: Oral Paper:Papers for Sections
Date: Tuesday, July 29th, 2008
Time: 3:00 PM